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Clinical and brain correlates to mindfulness meditation in individuals with history of depression


Lead researcher: Rael Cahn, MD, PhD
Faculty sponsor: Roger Walsh, MD, PhD

Purpose of study: To assess the efficacy of mindfulness meditation as taught in Mindfulness Based Cognitive Therapy (MBCT) for individuals with a history of depression on measures of depression, anxiety, and psychological well being as well as brain activity as assessed by electroencephalography (EEG), a non-invasive procedure that measures the electrical activity of the brain

Compensation: Subjects will be enrolled for free in an 8-week mindfulness meditation course which normally costs approximately $300-400 when taken in the community.

Eligibility: Adults between the ages of 18 and 65 that are fluent in English and meet the criteria for a history of major depressive disorder.  Participants must not currently in the midst of a full depressive episode but can have some continued depression symptoms and may either be on antidepressant medications or not.

Time commitment: Two visits to the lab to record the EEG and psychological state over a period of 9-10 weeks with an 8-week mindfulness meditation course in between the two laboratory visits.  Each weekly mindfulness meditation class is approximately 2.5hrs in duration and will be held at the Susan Samueli Center for Integrative Medicine in Irvine, CA and each of the two laboratory visits is 3 to 4 hours long and will take place at the UC Irvine main campus. 

The mindfulness meditation classes will be on Wednesday evenings and the first class will start on May 7 and end on June 25, 2014.

Dr. Rael Cahn, Department of Psychiatry and Human Behavior
714-456-8768 and